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Characteristic Skin Eruptions with a Distinct Histological Pattern Allow Early Diagnosis of Vitamin C Deficiency
Goran Mirkovic1, Markus Reinhold Mutke1, Beda Muehleisen2
1Department of Internal Medicine, University Hospital Basel, Basel, Switzerland.
Introduction:
Scurvy has become a rare disease in western countries with potentially high morbidity. Early diagnosis is crucial and can be challenging.
Case Presentation:
We present the case of a 56-year-old male patient who developed hemorrhagic diathesis after trivial impact trauma. Previously, the patient suffered from fatigue and loss of appetite. Characteristic skin eruptions and a distinct skin histology along with a decreased serum vitamin C level led to the diagnosis of scurvy. Following vitamin C supplementation, symptoms improved rapidly.
Conclusion:
In conclusion, vitamin C deficiency should be considered in cases with unclear hemorrhagic diathesis and a medical history of nutritional irregularities. Especially in cases of scurvy that do not yet show the full clinical spectrum of symptoms or have only moderately decreased serum vitamin C levels, thorough clinical dermatological examination and a skin biopsy are essential for early diagnosis and to prevent complications.
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