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Fatal asphyxia due to large laryngeal granuloma
Ajay Kumar1, Ravi Rautji2, Asit Ranjan Mridha3
1All India Institute of Medical Sciences, Department of Forensic Medicine & Toxicology, New Delhi, Delhi, India.
Autopsy & Case Reports
|July 18, 2024
Summary
Laryngeal granulomas, often caused by intubation, can lead to serious voice changes and breathing difficulties. In rare cases, these benign lesions can be fatal, as seen in a case following laryngeal polyp removal.
Area of Science:
- Otolaryngology
- Pathology
Background:
- Laryngeal granulomas, including vocal process or post-intubation granulomas, are benign inflammatory lesions.
- Etiologies include chronic irritation from endotracheal intubation, vocal cord trauma, and gastroesophageal reflux disease.
Observation:
- These lesions can develop postoperatively following mucosal injury from orotracheal intubation.
- Clinical signs such as voice alteration and dyspnea may manifest 1-4 months after extubation.
Findings:
- Laryngeal granulomas, though typically benign, carry a risk of airway compromise, including asphyxia.
- A rare fatal case of glottic granuloma occurred post-surgery for a laryngeal polyp, linked to prior intubation injuries.
Implications:
- Highlights the potential severity of laryngeal granulomas, even after initial treatment.
- Underscores the importance of recognizing granuloma risks associated with intubation history.
- Suggests vigilance for delayed airway complications in patients with relevant intubation history.
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