A Rare Atypical Intrapericardial Prostate Adenocarcinoma Metastasis With 68 Ga-PSMA-11 PET/CT

Area of Science:

• Oncology
• Nuclear Medicine
• Radiology

Background:

• Prostate cancer staging is crucial for treatment planning.
• Gallium-68 prostate-specific membrane antigen-11 (68Ga-PSMA-11) PET/CT is a key imaging modality for prostate cancer.
• Metastatic patterns of prostate cancer can vary, with some sites being more common than others.

Observation:

• An 88-year-old male patient with newly diagnosed prostate cancer underwent staging.
• 68Ga-PSMA-11 PET/CT demonstrated expected primary tumor uptake and common metastatic sites.
• Unusual findings included pulmonary lymphangitic carcinomatosis and a rare intrapericardial metastasis.

Findings:

• The PET/CT scan confirmed primary prostate cancer.
• Widespread metastatic disease was identified, including lymphadenopathy and bone metastases.
• A significant finding was an intrapericardial metastasis, an exceptionally rare location for prostate cancer.

Implications:

• This case underscores the importance of comprehensive staging in prostate cancer.
• The identification of rare metastatic sites like intrapericardial involvement expands our understanding of prostate cancer dissemination.
• Advanced imaging techniques like 68Ga-PSMA-11 PET/CT are vital for detecting even uncommon metastatic patterns.