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Updated: Jun 20, 2025

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Author Spotlight: Accelerating Discovery in Microporous Material Chemistry
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Profhilo® Structura, Current Status and Future Perspectives: A Practical Review.
Riccardo Forte1,2,3, Giovanni Salti1,2,3, Antonello Tateo1,2,3
1Riccardo Forte, MD , is a physician in Private Practice, Como, Italy and Lugano, Switzerland.
Plastic and Aesthetic Nursing
|July 19, 2024
Summary
Profhilo® Structura, a new hyaluronic acid injectable, effectively restores facial adipose tissue in the cheeks using unique NAHYCO® technology. This treatment offers lipolifting and tightening, addressing aging signs safely and effectively.
Area of Science:
- Aesthetic medicine
- Dermatology
- Cosmetic surgery
Background:
- Hyaluronic acid (HA) injectables are popular for anti-aging treatments.
- Facial aging involves changes in adipose tissue, particularly in the cheeks.
- Profhilo® Structura utilizes novel nano hybrid complex of hyaluronic acid (NAHYCO)® technology.
Purpose of the Study:
- To establish clinical rationale and guidelines for using Profhilo® Structura.
- To describe optimal injection techniques for treating specific facial fat compartments.
- To evaluate clinical outcomes for restoring facial adipose tissue.
Main Methods:
- Expert discussion on clinical rationale and techniques.
- Development of injection strategies for preauricular and zygomatic areas.
- Application of Profhilo® Structura in patients with fat hypotrophy or jowl sagging.
Main Results:
- Profhilo® Structura demonstrated effective restoration of facial adipose tissue.
- Optimal injection techniques maximized product diffusion and minimized risks.
- Treatment resulted in lateral tightening and lipolifting effects.
Conclusions:
- Profhilo® Structura is the first HA injectable to integrate and restore adipose tissue.
- The product offers a safe and effective solution for facial fat restoration.
- Expert-guided techniques ensure optimal outcomes in treating aging-related fat compartment changes.
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