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Updated: Jun 20, 2025

Author Spotlight: Unraveling the Molecular Mechanisms in PCO and Fibrosis Following Cataract Surgery
Published on: December 1, 2023
ENDOSCOPIC SURGERY FOR CONGENITAL OR ACQUIRED CATARACT ASSOCIATED WITH PERSISTENT FETAL VASCULATURE: A CASE SERIES
Mitsuru Otsubo1,2, Tatsushi Kaga1, Yoshimi Yokoyama1
1Department of Ophthalmology, Community Health Care Organization Chukyo Hospital, Aichi, Japan.
Purpose:
Persistent fetal vasculature (PFV) is a congenital malformation caused by a failure in regression of the primary vitreous and hyaloid vessels. An abnormal PFV occurs in the anterior and posterior segments of the eye. Surgery for PFV carries the risk of retinal detachment. The authors report four cases of cataracts associated with PFV, in which their novel surgical technique with an intraocular endoscope was safely performed.
Methods:
Lensectomy and vitrectomy were performed in Cases 1, 3, and 4, while lensectomy, vitrectomy, and intraocular lens implantation using an endoscope were performed in Case 2. In all cases, after lens removal, a slit at the posterior lens capsule was created to avoid the retrolental fibrovascular membrane using underwater electric coagulation. Moreover, the endoscope was inserted, by which the intraocular region was observed to determine the treatment method for the fibrovascular membrane and vitreous stalk. No additional surgeries were required for complications before or after any of the surgeries.
Results:
Using an endoscope during cataract surgery associated with PFV, observing the vitreous stalk at high magnification and ensuring safe treatment were possible.
Conclusion:
Endoscopic surgery could be considered an effective method for treating PFV-associated cataracts.

