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Intergenerational Effects Of Racism On Amygdala And Hippocampus Resting State Functional Connectivity.

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Intergenerational Effects Of Racism On Amygdala And Hippocampus Resting State Functional Connectivity.

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Intergenerational effects of racism on amygdala and hippocampus resting state functional connectivity.

T R A Kral^1,2, C Y Williams^1,3, A C Wylie^4,5

¹Center for Healthy Minds, University of Wisconsin -Madison, Madison, WI, USA.

Scientific Reports

|July 23, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Maternal experiences of racism impact infant brain development. Higher maternal racism exposure correlated with altered neural connectivity in neonates, suggesting a biological pathway for intergenerational trauma transmission.

Keywords:

Amygdala Functional connectivity Hippocampus Racism Trauma

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Area of Science:

Neuroscience
Developmental Psychology
Sociology

Background:

Racism significantly affects the mental health of BIPOC individuals.
The intergenerational impact of racism-related trauma on offspring neurodevelopment is not well understood.
Research is needed to explore biological pathways linking maternal racism experiences to infant brain development.

Purpose of the Study:

To investigate the association between maternal experiences of racism and neonatal resting-state functional connectivity (rsFC).
To examine potential biological pathways for the intergenerational transmission of racism-related trauma.
To explore how maternal racism exposure may influence infant neurodevelopment.

Main Methods:

Analyzed rsFC in 25 neonates (BIPOC mothers).

Used Experiences of Racism Scale scores as a regressor in seed-based connectivity analyses focusing on the amygdala and hippocampus.

Controlled for infant sex and gestational age.

Main Results:

Maternal racism experiences were linked to stronger amygdala rsFC with the visual cortex and thalamus in neonates.
Higher maternal racism exposure correlated with stronger hippocampus rsFC with the visual cortex and a temporo-parietal network.
Findings suggest a biological link between maternal racism and infant neural connectivity.

Conclusions:

Maternal experiences of racism may alter offspring neurodevelopment through changes in brain connectivity.
This study provides evidence for a biological pathway of intergenerational racism-related trauma.
Results have implications for social policy and interventions addressing racism's impact on child development.