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[Anatomicopathological findings relating to fungal infections: considerations on their increase and microbiological
Abstract:
2,366 consecutive autopsies carried out at the Institute of Anatomy and Histopathology of the University of Genova over the last 10 years are re-examined. 33 cases of visceral mycosis were found (a frequency of 1.4%). The following factors were considered: number and location of fungal infection, morphological characteristics of mycetes responsible, host tissue reaction, relationship with any other disease manifestation or predisposing factors. It is emphasized that these infections are increasing in frequency and severity. Clinics should therefore always consider possible fungal causes in the differential diagnosis of infections.
Insights
Visceral mycosis, fungal infections affecting internal organs, are increasingly frequent and severe. Autopsy data revealed a 1.4% incidence, highlighting the need for clinical consideration in differential diagnoses.
Area of Science:
- Pathology
- Mycology
- Infectious Diseases
Background:
- Visceral mycosis, or internal fungal infections, presents diagnostic challenges.
- Understanding the epidemiology and characteristics of these infections is crucial for patient care.
Purpose of the Study:
- To re-examine autopsy data to determine the frequency and characteristics of visceral mycosis.
- To identify factors associated with fungal infections and their severity.
Main Methods:
- Analysis of 2,366 consecutive autopsies performed over 10 years.
- Detailed examination of 33 identified cases of visceral mycosis.
Main Results:
- A frequency of 1.4% for visceral mycosis was observed in the autopsy cohort.
- Factors such as infection location, fungal morphology, and host response were analyzed.
Conclusions:
- Visceral mycosis is an increasing concern in terms of frequency and severity.
- Clinicians should consider fungal infections in the differential diagnosis of unexplained illnesses.