Related Experiment Video
Updated: May 5, 2026

Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging
Published on: April 6, 2014
SECONDARY MULTIPLE EVANESCENT WHITE DOT SYNDROME AFTER BLUNT TRAUMA
Samantha R Goldburg1,2, Jennifer Adeghate3, Gaetano R Barile1,2,4
1Department of Ophthalmology, Northwell, New Hyde Park, New York.
A rare case of Multiple Evanescent White Dot Syndrome (MEWDS) occurred two years after blunt eye trauma. This delayed presentation of MEWDS following trauma highlights a longer latency period than previously documented.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Neuro-ophthalmology
Background:
- Multiple Evanescent White Dot Syndrome (MEWDS) is an idiopathic inflammatory condition affecting the outer retina.
- While often unilateral and self-limiting, its association with specific triggers is being increasingly recognized.
Purpose of the Study:
- To document a unique case of secondary unilateral MEWDS.
- To highlight the delayed onset of MEWDS following blunt ocular trauma.
Main Methods:
- An observational case report detailing a single patient's presentation and clinical course.
- Ophthalmic examination, including best-corrected visual acuity (BCVA) and optical coherence tomography (OCT).
Main Results:
- A 25-year-old male developed MEWDS two years after blunt force trauma to the eye.
- Initial symptoms included decreased vision, iritis, commotio retinae, and pigment epithelial detachment.
- Subsequent examination revealed characteristic white dot lesions, ellipsoid zone disruption, and significant visual recovery within two months of observation.
Conclusions:
- This case represents a significantly longer latency period between blunt eye trauma and the onset of MEWDS than previously reported.
- The findings suggest that blunt trauma may be a trigger for MEWDS even with a substantial delay.
More Related Videos
08:25Intravital Imaging of Fluorescent Protein Expression in Mice with a Closed-Skull Traumatic Brain Injury and Cranial Window Using a Two-Photon Microscope
Published on: April 21, 2023
04:02Author Spotlight: Developing Precise and Clinically Relevant Models for Studying Secondary Degeneration in Traumatic Optic Neuropathy
Published on: November 29, 2024
Related Concept Videos
Hemorrhagic Stroke ll: Pathophysiology
Traumatic Brain Injury l: Introduction
Cerebral Edema ll: Pathophysiology
Secondary Spinal Cord Injury llI: Pathophysiology