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Updated: Jul 16, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Left Ventricular Outflow Tract and Transcatheter Mitral Valve Replacement Obstruction and TMVR: Predictors,
1Division of Cardiology, University of Washington School of Medicine, Seattle, Washington, USA.
Transcatheter mitral valve replacement can cause left ventricular outflow tract obstruction. This review covers predictors, assessment strategies, and emerging treatments for this complication.
Area of Science:
- Cardiology
- Interventional Cardiology
- Structural Heart Disease
Background:
- Left ventricular outflow tract obstruction (LVOTO) is a potential complication following transcatheter mitral valve replacement (TMVR).
- Accurate prediction and management of LVOTO are crucial for successful TMVR outcomes.
- Advances in TMVR necessitate updated understanding of associated complications.
Purpose of the Study:
- To review current knowledge on LVOTO in the context of TMVR.
- To highlight predictors and assessment strategies for LVOTO.
- To discuss evolving management approaches for LVOTO.
Main Methods:
- Review of high-impact presentations from Transcatheter Valve Therapies 2023.
- Synthesis of expert insights on LVOTO predictors and assessment.
- Compilation of information on current and developing management strategies.
Main Results:
- Established predictors for LVOTO have been identified.
- A consensus strategy for preprocedure assessment of LVOTO risk exists.
- Multiple management strategies for LVOTO are under investigation and development.
Conclusions:
- Understanding LVOTO is critical for safe and effective TMVR.
- Preprocedure assessment and risk stratification are key to mitigating LVOTO.
- Ongoing research promises improved therapeutic options for TMVR-associated LVOTO.
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