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Updated: Jun 17, 2025

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
Published on: April 30, 2020
TB prevention activities in the WHO European Region
A Matteelli1, Z Mkrtchyan2, T Masini3
1Institute of Infectious and Tropical Diseases, WHO Collaborating Centre for Tuberculosis Prevention, University of Brescia, Brescia, Italy.
The European Prevention and Systematic Screening Initiative to End TB (PASS) survey reveals that while TB preventive treatment policies align with WHO guidelines, implementation lags behind. Accelerating efforts requires significant investment and coordinated action across Europe.
Area of Science:
- Public Health
- Infectious Disease Control
- Health Policy
Background:
- Tuberculosis (TB) preventive treatment (TPT) is crucial for preventing progression from TB infection to disease.
- The WHO European Prevention and Systematic Screening Initiative to End TB (PASS) aims to scale up TPT management.
- A baseline assessment was needed to monitor TPT intervention scale-up due to the lack of a monitoring system.
Purpose of the Study:
- To conduct a baseline assessment of TB preventive activities in the WHO European Region.
- To provide a reference point for monitoring the scale-up of TPT interventions under the PASS initiative.
Main Methods:
- A semi-structured survey with 52 questions was administered.
- The survey was distributed to focal points across 55 countries/territories in the European Region via LimeSurvey.
- Data collection occurred between September and October 2023, covering TPT, systematic screening, and infection control.
Main Results:
- A 51% response rate was achieved with 28 questionnaires returned.
- National policies for TPT and TB screening generally align with WHO guidelines.
- Significant gaps exist in the implementation of TB screening, prevention, and infection control activities.
Conclusions:
- The PASS initiative will target identified areas to accelerate progress towards 2027 UN High-Level Meeting targets for TB prevention.
- A substantial scale-up of efforts, increased investment, and coordinated interventions are necessary.
- Addressing the entire prevention cascade, from population identification to treatment completion, is essential.
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