Detection of corneal pathology among Indians using WBC count as inflammatory marker

The multifaceted role of NLR as a biomarker in corneal pathologies, aiming to enhance clinicians' understanding for better patient outcomes is of interest. An extensive ophthalmic assessment was conducted. Patients with corneal pathologies were identified as cases and those with healthy cornea as controls. A complete WBC blood count was performed using Automated Flow Cytometric method and the counts of white blood cells, neutrophils, platelets, and lymphocytes where recorded. NLR, PLR, and MLR were calculated by dividing the Neutrophil/Platelet/Monocyte counts by the lymphocyte counts. The study revealed that the Neutrophil-to-Lymphocyte Ratio (NLR), Monocyte-to-Lymphocyte Ratio (MLR), and Platelet-to-Lymphocyte Ratio (PLR) were significantly higher in the case group compared to the control group. N/L proved the best predictor among inflammatory markers, followed by M/L and P/L, highlighting the intricate immune response in corneal diseases, urging customized assessments in ocular health research.