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Microencapsulation of natural products using spray drying; an overview.
Mahshid Mardani1,2, Saeed Siahtiri3, Masoud Besati2
1Department of Civil, Construction and Environmental Engineering, University of Alabama, Tuscaloosa, AL, USA.
Journal of Microencapsulation
|August 12, 2024
Summary
Microencapsulation enhances natural compound stability for pharmaceutical use. Spray drying is a key method, improving compound protection and extending product shelf life.
Area of Science:
- Pharmaceutical Science
- Materials Science
Background:
- Natural compounds offer therapeutic benefits but often exhibit poor stability.
- Environmental factors degrade natural compounds, limiting their pharmaceutical applications.
Purpose of the Study:
- To investigate microencapsulation as a strategy to improve natural compound stability.
- To evaluate different microencapsulation techniques for pharmaceutical applications.
Main Methods:
- Comparison of microencapsulation techniques: spray drying, freeze drying, and coacervation.
- Focus on spray drying due to its advantages for natural compound stabilization.
Main Results:
- Microencapsulation significantly enhances the stability of natural compounds.
- Spray drying yields varied morphologies, sizes, and encapsulation efficiencies.
- Benefits include controlled release, taste masking, degradation protection, and extended shelf life.
Conclusions:
- Microencapsulation, especially spray drying, is a viable method to overcome natural compound instability.
- This technique broadens the pharmaceutical applications of natural compounds by improving protection and shelf life.
