Related Experiment Video
Updated: Jun 16, 2025
13:13
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
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Reply to 'Adrenomedullin as a marker of hypoxia, not hypoperfusion'
Geert H D Voordes1, Gad Cotter1, Adriaan A Voors1
1Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands.
European Journal of Heart Failure
|August 20, 2024
Abstract
No abstract available in PubMed .
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Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits. Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
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01:23Hypoxia
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Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
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Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
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