Related Experiment Video
Updated: Jun 14, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain PPOP
Published on: January 27, 2010
Prognostic Factors on Preoperative MRI for Patient-Reported Outcomes After Posterior Medial Meniscus Root Repair.
Sergio E Flores1, Rawee Manatrakul2,3, Christopher Anigwe1
1Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA.
Preoperative medial tibial bone marrow edema-like lesions (MT-BMELL) on MRI predict worse outcomes after posterior medial meniscus root (PMMR) repair. Identifying these factors can guide patient expectations and treatment strategies for PMMR tears.
Area of Science:
- Orthopedic Surgery
- Radiology
- Sports Medicine
Background:
- Posterior medial meniscus root (PMMR) tears can be effectively treated with surgical repair, potentially delaying knee osteoarthritis progression.
- However, limited data exists on prognostic factors influencing outcomes after PMMR repair.
Purpose of the Study:
- To identify preoperative magnetic resonance imaging (MRI) factors predicting patient-reported outcomes (PROs) after PMMR repair.
- Hypothesized that increased degenerative changes on MRI correlate with poorer PROs.
Main Methods:
- Retrospective cohort study (Level of evidence, 3) of 29 patients with PMMR repair and minimum 2-year follow-up.
- Preoperative MRIs were assessed for meniscus, cartilage, bone marrow edema-like lesions (BMELL), and meniscal extrusion using the Whole-Organ Magnetic Resonance Imaging Score.
- Postoperative outcomes included visual analog scale (VAS) pain scores and PRO surveys (e.g., Knee injury and Osteoarthritis Outcome Score - KOOS).
Main Results:
- Significant VAS pain reduction post-surgery (4.9 to 1.6, P < .001).
- Patient Acceptable Symptom State (PASS) achievement varied by KOOS subscale (44.8%–72.4%).
- Patients with medial tibial BMELL (MT-BMELL) showed significantly lower KOOS Symptoms scores (P = .032).
Conclusions:
- Preoperative MT-BMELL on MRI is associated with worse KOOS Symptoms scores following PMMR repair.
- Cartilage quality and meniscal extrusion did not significantly impact outcomes.
Related Concept Videos
Magnetic Resonance Imaging
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies for Cardiovascular System IV: CMRI
Imaging Studies IV: Magnetic Resonance Imaging

