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Updated: Jun 15, 2025

Author Spotlight: Revolutionizing Research on Vaginal Microbiome Interactions Using a Vaginal Chip
Published on: February 16, 2024
The microbiome effect on the female reproductive performance
Ricardo Zanella1, Janine de Camargo1, Claudia Almeida Scariot1
1Programa de Pós-graduação em BioExperimentação, Escola de Ciências Agrárias Inovação e Negócios, Universidade de Passo Fundo, Passo Fundo, RS, Brasil.
Abstract:
The female reproductive function is coordinated by the endocrine system driven by the hypothalamic-pituitary-gonadal (HPG) axis. While not directly part of the female reproductive system, the gut microbiome plays a crucial role in overall health, including reproductive health. The gut microbiome communicates bidirectionally with the brain via the gut-brain axis, influencing stress levels, mood, and hormonal balance, which can impact reproductive health and fertility. In addition to that, the vaginal and uterine microbiome are directly involved with the reproductive success of farm animals, including female fertility and offspring development. In this paper, we summarize some of the effects of bacterial contamination in the female reproductive tract and their association with reproductive performance in farm animals.
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