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Related Concept Videos

Crossover Experiments01:16

Crossover Experiments

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Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
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Study Design in Statistics01:15

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A study design is a set of techniques that allow a researcher to collect and analyze data from different variables defined for a specific research problem. Statistics is commonly for effective study design and more robust experiments,
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Experimental Designs01:16

Experimental Designs

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An experimental design is a systematic process that allows researchers to evaluate the relationship between dependent and independent variables. There are three widely used types of experimental design - pre-experimental design, true experimental design, and quasi-experimental design. In pre-experimental design, the researcher compares the data before and after some interventions or treatments. The true-experimental design has more than one purposefully created group, a commonly measured...
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Study Designs in Epidemiology

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Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
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Cochran's Q Test01:17

Cochran's Q Test

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Cochran's Q Test is a nonparametric statistical test used to determine if there are potential differences in the outcomes of three or more related groups on a binary (yes/no) or dichotomous outcome. It is essentially an extension of the McNemar Test, which is limited to two related samples - Cochran's Q test can handle three or more related samples, making it more versatile in scenarios where subjects are measured under multiple conditions. The test statistic follows a Chi-Square...
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Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I,...
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An Introduction to the Crossover Trial Design.

Bernadette Capili1, Joyce K Anastasi

  • 1Bernadette Capili is director of the Heilbrunn Family Center for Research Nursing at Rockefeller University, New York City, and Joyce K. Anastasi is the Independence Foundation Professor of Nursing and founding director of Special Studies in Symptom Management at New York University. This manuscript was supported in part by grant No. UL1TR001866 from the National Institutes of Health's National Center for Advancing Translational Sciences Clinical and Translational Science Awards Program. Contact author and column coordinator: Bernadette Capili, bcapili@rockefeller.edu . The authors have disclosed no potential conflicts of interest, financial or otherwise.

The American Journal of Nursing
|August 26, 2024
PubMed
Summary
This summary is machine-generated.

This article series provides nurses with essential knowledge for clinical research and evidence-based practice. It covers key concepts from research design to data interpretation, serving as a valuable resource.

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Area of Science:

  • Nursing Research
  • Evidence-Based Practice

Background:

  • This is the 23rd article in a series focused on clinical research for nurses.
  • The series aims to equip nurses with fundamental research concepts and principles.

Purpose of the Study:

  • To serve as a comprehensive resource for nurses in understanding clinical research.
  • To elucidate the core concepts underpinning evidence-based practice.

Main Methods:

  • The series presents concepts sequentially, covering research design.
  • Data interpretation principles are also discussed.

Main Results:

  • Nurses will gain a foundational understanding of research methodologies.
  • The series facilitates the application of research findings in clinical settings.

Conclusions:

  • This article series is a vital educational tool for nurses.
  • It empowers nurses to engage with and utilize research effectively in their practice.