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Could Vaccination against COVID-19 Trigger Immune-Mediated Inflammatory Diseases?
Aikaterini I Liakou1, Andreas G Tsantes2,3, Eleni Routsi1
11st Department of Dermatology-Venereology, "Andreas Sygros" Hospital, National and Kapodistrian University of Athens Medical School, 16121 Athens, Greece.
Abstract:
Exacerbations and new onset of immune-mediated inflammatory diseases, such as psoriasis and hidradenitis suppurativa, have been reported following COVID-19 vaccination. In patients with hidradenitis suppurativa, recent studies have shown that those who received mRNA vaccines were 3.5 times as likely to develop flares following vaccination compared to patients who received non-mRNA vaccines, indicating that mRNA COVID-19 vaccines are associated with hidradenitis suppurativa flares. Similar findings have been found in other studies evaluating the association between COVID-19 vaccines and other immune-mediated inflammatory diseases such as psoriasis, atopic dermatitis, lichen planus, and alopecia areata. However, further research is warranted in larger populations to validate these findings.
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