Related Experiment Video
Updated: Jun 14, 2025

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Inverted Papilloma: A Practical Approach to Diagnosis, Management, and Current Controversies
1Department of ENT-HNS, Kathmandu University Hospital, Dhulikhel Hospital, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.
Inverted papilloma (IP) is a rare sinonasal tumor with aggressive behavior and high recurrence risk. Treatment involves surgery, with endoscopic or external approaches depending on tumor extent, and requires diligent follow-up for recurrence detection.
Area of Science:
- Otolaryngology
- Oncology
- Pathology
Background:
- Inverted papilloma (IP) is an uncommon sinonasal tumor.
- It exhibits locally aggressive behavior, high recurrence rates, and malignant transformation potential.
- Human papillomavirus (HPV) is implicated in up to 40% of cases, though etiology is unclear.
Purpose of the Study:
- To summarize the key characteristics of inverted papilloma.
- To outline current treatment strategies and follow-up protocols for sinonasal inverted papilloma.
Main Methods:
- Review of existing literature on sinonasal inverted papilloma.
- Analysis of epidemiological, etiological, clinical, and therapeutic aspects.
Main Results:
- IP primarily affects middle-aged adults.
- Surgical intervention is the primary treatment modality.
- Treatment approach (endoscopic vs. external) depends on tumor characteristics and extent.
Conclusions:
- IP requires surgical management with tailored approaches.
- Long-term, rigorous follow-up is essential for early detection of recurrence.
- Understanding IP's behavior is crucial for effective patient management.
Related Concept Videos
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Peptic Ulcer Disease IV: Management
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...

