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FUNCTIONAL STATE OF THE REPRODUCTIVE SYSTEM AFTER UNILATERAL OOPHORECTOMY
S Dzotsenidze1, L Pkhaladze1, J Kristesashvili1
11Department of Obstetrics, Gynecology and Reproductology, Ivane Javakhishvili Tbilisi State University, Georgia.
Georgian Medical News
|September 4, 2024
Summary
Unilateral oophorectomy temporarily reduces ovarian reserve. Reproductive function recovers within a year for younger women, but not for those in late reproductive age, necessitating regular monitoring.
Area of Science:
- Reproductive endocrinology
- Gynecology
- Oncology
Background:
- Unilateral oophorectomy (UO) is a surgical procedure involving the removal of one ovary.
- Assessing the impact of UO on reproductive system function is crucial for patient management.
Purpose of the Study:
- To evaluate the functional status of the reproductive system after unilateral oophorectomy across different age groups.
- To determine the recovery of ovarian function and hormone levels post-surgery.
Main Methods:
- Forty-three patients aged 7–38 years underwent UO and were categorized into three age-based groups.
- Reproductive system function was assessed at 3 months and 1 year post-surgery, including Anti-Müllerian Hormone (AMH) levels.
Main Results:
- Post-UO, functional cysts developed in the remaining ovary in 69.8% of patients, more frequently in the oldest group.
- AMH levels significantly decreased 3 months after UO in all groups.
- AMH levels recovered within one year for patients aged 7–30 years but remained low for those aged 30–38 years.
Conclusions:
- UO causes a transient decrease in ovarian reserve across all ages.
- Functional ovarian activity is restored within one year for pubertal and early reproductive-aged women.
- Late reproductive-aged women do not show AMH recovery post-UO, and functional cysts are common, requiring regular follow-up.
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