Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.0K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.0K
Preclinical Development: Overview01:28

Preclinical Development: Overview

4.3K
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
4.3K
Common Respiratory Disorders01:31

Common Respiratory Disorders

345
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
345
Principles of Disease Surveillance01:26

Principles of Disease Surveillance

77
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
77
Learning Disabilities01:25

Learning Disabilities

92
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
92
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

114
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
114

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incomplete Immunity for Varicella and Measles in Pediatric Organ Transplant Candidates. Real World Experience From an Infectious Diseases Pre-Transplantation Clinic.

Pediatric transplantation·2024
Same author

A descriptive study on multisystem inflammatory syndrome in children in a single center in West Michigan.

Pediatric rheumatology online journal·2021
Same author

Respiratory syncytial virus seropositivity at birth is associated with adverse neonatal respiratory outcomes.

Pediatric pulmonology·2020
Same author

Keeping the wolf at bay: Infection prevention and control measures for inpatient psychiatric facilities in the time of COVID-19.

General hospital psychiatry·2020
Same author

Respiratory syncytial virus exhibits differential tropism for distinct human placental cell types with Hofbauer cells acting as a permissive reservoir for infection.

PloS one·2019
Same author

Optimal Timing of Repeat Multiplex Molecular Testing for Respiratory Viruses.

Journal of clinical microbiology·2019

Related Experiment Video

Updated: Jun 14, 2025

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
09:14

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

Published on: January 26, 2019

10.8K

The RSV roadmap in children: Lessons learned, paths forward.

Ruchita Negi1, Jonathan Shabab1, Frank Esper2

  • 1Center for Pediatric Infectious Diseases, Department of Pediatrics. Cleveland Clinic Children's, Cleveland, OH.

Cleveland Clinic Journal of Medicine
|September 4, 2024
PubMed
Summary
This summary is machine-generated.

New vaccines and monoclonal antibodies offer significant protection against respiratory syncytial virus (RSV) for infants. These advancements promise to reduce severe RSV illness, including bronchiolitis and pneumonia, globally.

More Related Videos

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

15.4K
An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
09:01

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

Published on: December 10, 2013

7.9K

Related Experiment Videos

Last Updated: Jun 14, 2025

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
09:14

An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay

Published on: January 26, 2019

10.8K
Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

15.4K
An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
09:01

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

Published on: December 10, 2013

7.9K

Area of Science:

  • Virology and Immunology
  • Pediatric Infectious Diseases
  • Vaccine Development

Background:

  • Respiratory syncytial virus (RSV) poses a significant global health threat to infants, causing severe lower respiratory tract infections like bronchiolitis and pneumonia.
  • Despite extensive research, effective prevention and treatment strategies for RSV have seen limited progress, with past vaccine attempts leading to enhanced disease.
  • Existing treatment options for RSV have demonstrated restricted efficacy in clinical settings.

Purpose of the Study:

  • To highlight recent breakthroughs in RSV prevention strategies targeting vulnerable infant populations.
  • To discuss the potential impact of novel maternal vaccines and monoclonal antibodies on reducing RSV burden.
  • To underscore the significance of advancements in vaccine development, particularly those focusing on the prefusion F glycoprotein.

Main Methods:

  • Review of recent clinical advancements in RSV prevention.
  • Analysis of maternal vaccine efficacy targeting the prefusion F glycoprotein.
  • Evaluation of monoclonal antibody administration for neonatal RSV protection.

Main Results:

  • Maternal vaccines targeting the prefusion F glycoprotein show substantial benefits in preventing severe RSV illness in infants.
  • Monoclonal antibodies provide immediate protection for newborns, effective within one week of birth.
  • These innovative approaches represent a significant shift in managing RSV.

Conclusions:

  • Recent innovations in maternal vaccines and monoclonal antibodies offer powerful tools for preventing severe RSV infections in infants.
  • These advancements hold the potential to drastically alter the global impact of RSV outbreaks.
  • Continued research and implementation of these strategies are crucial for protecting vulnerable infant populations.