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Author Spotlight: Unlocking the Mysteries of Oral Potential Malignancies
Published on: August 11, 2023
PANoptosis: a new insight for oral diseases
Xinyi Jiang1,2, Tingting Fu1,2, Lan Huang3,4
1Department of Orthodontics, Stomatological Hospital of Chongqing Medical University, #426 SongShiBeiRd., YuBei, Chongqing, 401147, People's Republic of China.
Abstract:
PANoptosis, a burgeoning area of research, is a unique type of programmed cell death typified by pyroptosis, apoptosis, and necroptosis, yet it defies singular classification by any one mode of death. The assembly and activation of PANoptosomes are pivotal processes in PANoptosis, with several PANoptosomes already identified. Linkages between PANoptosis and the pathophysiology of various systemic illnesses are established, with increasing recognition of its association with oral ailments. This paper aims to deepen understanding by conducting a comprehensive analysis of the molecular pathways driving PANoptosis and exploring its potential implications in oral diseases.
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