Related Experiment Video
Updated: Jun 14, 2025

Single-cell Microinjection for Cell Communication Analysis
Published on: February 26, 2017
Airineme-Mediated Intercellular Communication
1Department of Developmental and Cell Biology, University of California, Irvine, CA, USA. dseom@uci.edu.
Abstract:
Intercellular communication is indispensable across multicellular organisms, and any aberration in this process can give rise to significant anomalies in developmental and homeostatic processes. Thus, a comprehensive understanding of its mechanisms is imperative for addressing human health-related concerns. Recent advances have expanded our understanding of intercellular communication by elucidating additional signaling modalities alongside established mechanisms. Notably, cellular protrusion-mediated long-range communication, characterized by physical contact through thin and elongated cellular protrusions between cells involved in signal transmission and reception, has emerged as a significant intercellular signaling paradigm. This chapter delves into the exploration of a signaling cellular protrusion termed 'airinemes,' discovered in the zebrafish skin. It covers their identified signaling roles and the cellular and molecular mechanisms that underpin their functionality.
More Related Videos
Related Concept Videos
What is Cell Signaling?
Contact-dependent Signaling
Gap Junctions
In animal cells, gap junctions are formed...
Overview of Cell Signaling
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
Autocrine Signaling
Autocrine Signaling in Macrophages
Under normal physiological conditions, autocrine signaling is essential for maintaining homeostasis. This process is well characterized in...
Intracellular Signaling Affects Focal Adhesions
Some...
Paracrine Signaling

