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Related Concept Videos

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
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The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
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Related Experiment Video

Updated: Jun 13, 2025

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
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Whole Blood Program: Implementation in a Rural Trauma Center.

Lanny C Orr1, Alexa L Peterson, Tessa C Savell

  • 1Author Affiliations: Trauma Services, (Mr Orr, Mrs Peterson, Mrs Savell, Mrs McCotter, and Mr Palm); Lab-Blood Bank, (Mrs Arnold); Trauma & Critical Care Surgery, (Dr Riha); and Collaborative Science & Innovation, Billings Clinic, Billings, Montana (Dr Thompson).

Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses
|September 9, 2024
PubMed
Summary

Whole blood transfusions in rural trauma settings significantly reduced mortality compared to component therapy. This program offers vital care for severely injured patients, improving outcomes and reducing wastage.

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Area of Science:

  • Emergency Medicine
  • Transfusion Medicine
  • Trauma Surgery

Background:

  • Balanced transfusion of blood components is crucial for hemostatic resuscitation in trauma.
  • Previous studies on whole blood transfusion have primarily focused on urban trauma centers, leaving a gap in rural settings.

Purpose of the Study:

  • To compare the efficacy of component therapy versus whole blood therapy in terms of wastage rates and mortality within a rural trauma center setting.

Main Methods:

  • A nonrandomized, retrospective, observational study was conducted over three years (2020-2022) at a Level II trauma center.
  • Data from the trauma registry informed whole blood needs and supply sustainability.
  • Protocols for whole blood use were established, with monthly monitoring of utilization and laboratory compliance.

Main Results:

  • Mortality rates were significantly lower in patients receiving whole blood (8%) compared to those receiving component therapy (29%) (p = .030).
  • Wastage rates for whole blood decreased from 43.4% in 2021 to 38.7% in 2022.
  • Nurses found whole blood easier to administer and document, eliminating the need for ratio compliance.

Conclusions:

  • An evidence-based whole blood transfusion program can provide essential care for severely injured trauma patients in large rural regions.
  • This approach demonstrates improved patient outcomes and efficient resource management in a rural context.