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Harnessing the immune system: vaccines to fight neurodegenerative diseases

Alba Gonzalez-Artero1, Jordi Pujols1, Salvador Ventura2

  • 1Institut de Biotecnologia i de Biomedicina and Departament de Bioquímica i de Biologia Molecular, Universitat Autònoma de Barcelona, 08193 Bellaterra, (Barcelona), Spain.

Trends in Molecular Medicine
|September 10, 2024
PubMed

Neurodegenerative diseases strongly impact our aging society, with treatments providing only symptomatic relief. Recent advancements in active immunotherapy offer solutions by stimulating the immune system to produce antibodies against misfolded and toxic amyloid proteins. We discuss vaccines under clinical evaluation for Alzheimer's and Parkinson's diseases, highlighting successes and ongoing trials.

Keywords:
Alzheimer’s diseaseParkinson’s diseaseamyloid proteinsimmunotherapyneurodegenerative diseasesvaccines

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