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Related Experiment Videos

Pan-mandibular keratocyst with eosinophilia.

D S Gupta, M K Gupta, R M Borle

    International Journal of Oral Surgery
    |June 1, 1985
    PubMed
    Summary

    A rare case of a large keratocystic odontogenic tumor affecting the entire mandible, characterized by eosinophilia, is described. This extensive mandibular lesion presented with minimal signs or symptoms, making diagnosis challenging.

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    Area of Science:

    • Oral and Maxillofacial Surgery
    • Pathology
    • Dentistry

    Background:

    • Keratocystic odontogenic tumors (KOTs), formerly known as odontogenic keratocysts, are developmental cysts with a high recurrence rate.
    • These cysts typically occur in the posterior mandible but can affect any part of the jaws.

    Observation:

    • A unique case of a pan-mandibular KOT involving the entire mandible is presented.
    • The lesion exhibited significant eosinophilic infiltration within the cystic lining.
    • Notably, the extensive cystic lesion presented with no preponderant signs or symptoms.

    Findings:

    • The presented KOT is exceptionally large, encompassing the complete mandible.
    • The presence of eosinophilia within the KOT is an unusual histopathological finding.
    • The lack of overt clinical signs or symptoms in such an extensive lesion is highly atypical.

    Implications:

    • This case highlights the potential for KOTs to present as extensive, asymptomatic lesions, challenging early diagnosis.
    • The unusual eosinophilic nature warrants further investigation into potential etiological factors or specific KOT subtypes.
    • Understanding such rare presentations is crucial for accurate diagnosis and effective management of KOTs in clinical practice.

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