Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Phase Contrast and Differential Interference Contrast Microscopy

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Immunity-and-matrix-regulatory cells promote hyaline-like cartilage repair in osteoarthritis.

Bioactive materials·2026

Same author

Optimization of Thulium Fiber Laser Lithotripsy Efficacy Based on Multidimensional Parameter Combination Strategies.

European urology open science·2026

Same author

Revelations of pancreatic cancer treated by high-intensity focused ultrasound.

Discover oncology·2026

Same author

Differentiating benign from malignant pulmonary nodules in the context of bronchiectasis: a retrospective study.

Annals of medicine·2026

Same author

Stiff-yet-tough glassy hydrogels for tendon rupture repair.

Bioactive materials·2026

Same author

Uncovering the realities of suicidal ideation in older patients following lung cancer diagnosis: an interpretive phenomenological qualitative study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026

Same journal

Gaussian-modulated continuous-variable quantum key distribution over 60 km fiber using an integrated silicon photonic receiver.

Optics letters·2026

Same journal

E2E-OCT: end-to-end joint learning model using optical coherence tomography images for vocal cord leukoplakia diagnosis.

Optics letters·2026

Same journal

Holographic generation of panoramic 3D scenes by concave ellipsoidal mirror reflection.

Optics letters·2026

Same journal

Dual-pilot phase recovery with pair-wise maximum-ratio combining for coherent PONs.

Optics letters·2026

Same journal

Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

Optics letters·2026

Same journal

Quantitative estimation of deep-subwavelength scale via dark-field scattering axial energy concentration decay profiles.

Optics letters·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 13, 2025

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

Published on: February 12, 2014

Sequentially timed all-optical mapping photography with quantitative phase imaging capability.

Zhongxing Li, Long Xiao, Zonghao Feng

|September 13, 2024

Summary

This summary is machine-generated.

We combined diffraction phase microscopy (DPM) with STAMP to enable ultrafast, single-shot quantitative phase imaging. This powerful new method achieves trillions of frames per second for observing dynamic events.

More Related Videos

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Published on: January 28, 2019

Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM

Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM

Published on: December 1, 2016

Related Experiment Videos

Last Updated: Jun 13, 2025

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

Time Multiplexing Super Resolving Technique for Imaging from a Moving Platform

Published on: February 12, 2014

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Shaping the Amplitude and Phase of Laser Beams by Using a Phase-only Spatial Light Modulator

Published on: January 28, 2019

Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM

Three-dimensional Super Resolution Microscopy of F-actin Filaments by Interferometric PhotoActivated Localization Microscopy iPALM

Published on: December 1, 2016

Area of Science:

Optics and Photonics
High-Speed Imaging
Quantitative Phase Imaging

Background:

Sequentially Timed All-Optical Mapping Photography (STAMP) is valuable for observing dynamic events.
A key limitation of STAMP is its inability to capture quantitative phase images.
This restricts its application in analyzing transparent materials.

Purpose of the Study:

To integrate Diffraction Phase Microscopy (DPM) with STAMP.
To achieve ultrafast, single-shot quantitative phase imaging.
To overcome the limitations of traditional STAMP.

Main Methods:

Developed a hybrid system combining DPM and STAMP.
Achieved a record frame rate of up to 3.3 trillion frames per second (fps).
Utilized a custom-built phase module for system calibration and evaluation.

Main Results:

Successfully demonstrated single-shot quantitative phase imaging at unprecedented speeds.
Accurately captured the dynamic propagation of laser filamentation in air.
Validated the system's capability for high-resolution, high-speed phase measurements.

Conclusions:

The integration of DPM and STAMP provides a powerful new tool for ultrafast imaging.
This method significantly enhances STAMP's ability to measure highly transparent targets.
Opens new avenues for studying transient optical phenomena with quantitative phase information.