Contact Lens-Related Corneal Infections

Taylor J Linaburg1, Kristin M Hammersmith1

  • 1Department of Ophthalmology, University of Pennsylvania, Scheie Eye Institute, 51 North 39th Street, Philadelphia, PA 19104, USA.

Insights

Contact lens-associated microbial keratitis (MK) is a serious eye infection. Proper hygiene and avoiding overnight wear are crucial for preventing this vision-threatening condition.

Area of Science:

  • Ophthalmology
  • Microbiology

Background:

  • Microbial keratitis (MK) is a significant cause of vision impairment.
  • Contact lens wear is a primary risk factor for developing MK.

Purpose of the Study:

  • To provide an updated review of contact lens-associated microbial keratitis (CL-MK).
  • To discuss prevalence, risk factors, causative organisms, clinical presentation, and treatment strategies for CL-MK.

Main Methods:

  • Literature review of current research on contact lens-associated microbial keratitis.
  • Analysis of prevalence, risk factors, and etiological agents.
  • Summary of clinical manifestations and therapeutic approaches.

Main Results:

  • Bacterial pathogens are the most common cause of CL-MK, followed by fungi and protozoa.
  • Overnight wear, poor hygiene, and specific contact lens types increase MK risk.
  • Symptoms include pain, redness, and vision loss, varying with the causative organism.

Conclusions:

  • Preventive measures, including strict hygiene and avoiding overnight wear, are essential.
  • Prompt diagnosis and appropriate antimicrobial therapy (antibiotic, antifungal, antiprotozoal) are critical.
  • Surgical intervention is reserved for severe, non-responsive cases of CL-MK.

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