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Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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Related Experiment Video

Updated: Jun 13, 2025

Author Spotlight: Advancements in Impedance Monitoring for Cochlear Implant Surgery
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Author Spotlight: Advancements in Impedance Monitoring for Cochlear Implant Surgery

Published on: August 4, 2023

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Cochlear Implant Infections.

Patrick J Antonelli1

  • 1Department of Otolaryngology-Head and Neck Surgery, College of Medicine, University of Florida, 1345 Center Drive, M2-228 MSB, Box 100264, Gainesville, FL 32610-0264, USA.

Infectious Disease Clinics of North America
|September 14, 2024
PubMed
Summary
This summary is machine-generated.

Cochlear implants (CIs) can lead to various infections, posing unique risks due to their location and biofilm formation. This review outlines best practices for preventing and managing these CI-related infections.

Keywords:
Cochlear implantInfectionMeningitisPneumococcusStaphylococcusWound infection

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Area of Science:

  • Otolaryngology
  • Infectious Diseases
  • Biomedical Engineering

Background:

  • Cochlear implants (CIs) are susceptible to infections.
  • CI infections present unique challenges due to anatomical proximity to the respiratory tract and central nervous system.
  • Biofilm formation on CI devices is a significant concern.

Purpose of the Study:

  • To review infections associated with cochlear implants (CIs).
  • To discuss the specific considerations for CI-related infections.
  • To provide best practices for prevention and management in the absence of high-quality evidence.

Main Methods:

  • Literature review of infections related to cochlear implants.
  • Analysis of infection types including otitis media, mastoiditis, meningitis, and deep CI infection.
  • Synthesis of current knowledge to establish best practices.

Main Results:

  • Common CI infections include otitis media, mastoiditis, meningitis, and deep CI infections.
  • Unique risk factors for CI infections are related to device placement and biofilm formation.
  • Limited high-quality evidence exists for prevention and management strategies.

Conclusions:

  • Infections are a known complication of cochlear implants.
  • Proactive prevention and management strategies are crucial.
  • Best practice guidelines are provided to address the current evidence gap.