Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

172
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
172
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

134
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
134
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

225
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
225
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

313
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
313
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

214
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
214

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A broad-spectrum inhibitor of copper-exporting P<sub>1B</sub>-type ATPases.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Targeting SARS-CoV-2 main protease (3CL<sup>pro</sup>) with Paeonia-derived phytochemicals.

In silico pharmacology·2026
Same author

Assessment of Hypogonadism and Erectile Dysfunction in Males with Prediabetes: A Cross-Sectional Study from North India.

Indian journal of endocrinology and metabolism·2026
Same author

FDA-approved drug library screen identifies antidepressants, antimicrobials, anti-COPD, and anti-CVD agents as blockers of NLRP3 inflammasome and sepsis in a sex-dependent manner.

bioRxiv : the preprint server for biology·2026
Same author

Mechanistic insights and by-product analysis in sonocatalytic degradation of Orange-G dye molecule via potassium persulfate.

Scientific reports·2026
Same author

Flexible and printable thermoelectric films based on FeCl<sub>3</sub> doped P3HT.

Scientific reports·2026
Same journal

Ethical challenges in community-based tuberculosis screening and surveillance.

The Indian journal of tuberculosis·2026
Same journal

Effectiveness of e-learning modules in community-based tuberculosis awareness programs.

The Indian journal of tuberculosis·2026
Same journal

Role of digital media campaigns in improving TB health literacy at the community level.

The Indian journal of tuberculosis·2026
Same journal

Digital case-based learning for improving clinical decision-making in tuberculosis care.

The Indian journal of tuberculosis·2026
Same journal

Simulation and virtual reality applications in medical training for tuberculosis diagnosis.

The Indian journal of tuberculosis·2026
Same journal

Use of tele-education for strengthening community participation in tuberculosis control.

The Indian journal of tuberculosis·2026
See all related articles

Related Experiment Video

Updated: Jun 13, 2025

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis
06:26

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis

Published on: July 28, 2023

2.2K

Silico-tuberculosis: An updated review.

Swati Sharma1, Snehasish Nayak2, Bhavani R3

  • 1Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India; Viral Research and Diagnostic Laboratory, Department of Virology, Rajendra Memorial Research Institute of Medical Sciences (RMRIMS), Patna, Bihar, India.

The Indian Journal of Tuberculosis
|September 15, 2024
PubMed
Summary
This summary is machine-generated.

Silico-tuberculosis (silico-TB), a severe lung disease from silica dust exposure, requires integrated control strategies. Early diagnosis via CT scans and prompt anti-TB drug therapy are crucial for managing this global health concern.

Keywords:
Mycobacterium tuberculosis (MTB)Occupational hazardSilica dustSilico-TB

More Related Videos

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

13.9K
The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.0K

Related Experiment Videos

Last Updated: Jun 13, 2025

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis
06:26

Author Spotlight: Optimizing CFU Determination for Efficient Assessment of TB Vaccine Efficacy and Antigen Presentation Analysis

Published on: July 28, 2023

2.2K
A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
10:41

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA

Published on: April 30, 2020

13.9K
The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.0K

Area of Science:

  • Occupational Health
  • Pulmonary Medicine
  • Immunology

Background:

  • Silico-tuberculosis (silico-TB) is a serious global health issue resulting from combined tuberculosis and silicosis.
  • Occupational exposure to crystalline silica dust is the primary cause, exacerbated by weak safety regulations and limited healthcare access in low- and middle-income countries.

Purpose of the Study:

  • To provide a comprehensive review of silico-TB, covering its pathophysiology, clinical features, diagnostics, treatment, and challenges.
  • To highlight the need for updated knowledge and integrated control strategies for silico-TB.

Main Methods:

  • Literature review compiling updated knowledge on silico-TB.
  • Analysis of epidemiological data, pathophysiology, diagnostic techniques, and treatment protocols.

Main Results:

  • Silica impairs the immune system, promoting TB exacerbation by stimulating Th2 cells and M2 macrophages while inhibiting Th1 cells and M1 macrophages.
  • Chest CT scans are more effective than sputum or X-rays for early TB detection in silicosis patients.
  • Isoniazid and rifampicin minimize active TB risk in silicosis patients; 8-9 months of therapy prevents recurrence.

Conclusions:

  • Integrated silicosis and TB control initiatives are recommended to combat this dual health threat.
  • Improved monitoring, healthcare, safety regulations, and public education are essential for silico-TB prevention and management.