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Updated: Jun 13, 2025

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Overlooked Ventricular Septal Defect Post-Myocardial Infarction and Coronary Artery Bypass Grafting
Nderim Rexha1, Xhevdet Krasniqi1,2, Agnesa Dervishaj Rexha3
1Clinic of Cardiology, University Clinical Center of Kosova, Pristina, Kosovo, Albania.
Abstract:
Ventricular septal defect (VSD) represents a severe complication that may manifest after a myocardial infarction (MI), typically occurring between 2 and 7 days later. Due to advancements in reperfusion management, the incidence of VSDs after MI has become very rare, occurring in approximately 0.2% of MIs. The current guidelines recommend urgent post-infarction VSD (PI-VSD) closure. We report a case of a patient with a VSD, which was diagnosed 2.5 years after MI. At the time of acute inferior MI, the patient was managed with primary percutaneous intervention in the culprit artery, and 1 month later coronary artery by-pass grafting (CABG) was completed. Twenty and thirty months after AMI patient presented with ventricular tachycardia (VT). Following the second VT episode patient was hospitalized for further examination. Echocardiography revealed the presence of VSD at the site of inferioseptal wall aneurysm. An ICD was implanted owing to recurrent malignant rhythm disorders. In conclusion, although the PI-VSD might have been overlooked and the patient missed the chance of concomitant CABG and VSD repair, this case has reached a 3-year survival, which appears to be the longest survival recorded in a medically treated patient with PI-VSD.
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