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Updated: Jun 12, 2025

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Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
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Correlation between corrected carotid flow time and left ventricular outflow tract velocity-time integral using a
Issac Cheong1,2, Pablo Martín Merlo2, Francisco Marcelo Tamagnone2
1Department of critical care medicine, Sanatorio De los Arcos, Buenos Aires, Argentina.
Journal of Clinical Ultrasound : JCU
|September 18, 2024
Summary
Carotid corrected flow time (cCFT) strongly correlates with left ventricular outflow tract velocity-time integral (LVOT VTI) in ICU patients. This novel measurement can predict normal LVOT VTI, aiding hemodynamic monitoring.
Area of Science:
- Critical Care Medicine
- Cardiovascular Physiology
- Diagnostic Imaging
Background:
- Transthoracic echocardiography (TTE) is vital for ICU hemodynamic monitoring.
- Measuring left ventricular outflow tract velocity-time integral (LVOT VTI) assesses cardiac output.
- TTE in the ICU setting presents significant challenges.
Purpose of the Study:
- To investigate the relationship between carotid corrected flow time (cCFT) and LVOT VTI.
- To determine a cCFT threshold for predicting normal LVOT VTI.
Main Methods:
- Post-hoc analysis of a diagnostic accuracy study in a medical-surgical ICU.
- Phased array transducer used to measure cCFT and LVOT VTI.
- 22 ICU patients included (December 2021 - January 2022).
Main Results:
- Strong correlation found between LVOT VTI and cCFT (Spearman coefficient = 0.82, p < 0.0001).
- cCFT predicted LVOT VTI ≥ 17 cm with an AUC of 0.871.
- cCFT > 283 ms demonstrated 93.3% sensitivity and 85.7% specificity for predicting normal LVOT VTI.
Conclusions:
- cCFT shows a strong correlation with LVOT VTI.
- cCFT effectively predicts normal LVOT VTI in critically ill patients.
- Larger studies are needed to confirm these findings.

