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BiX3-Mediated Hydrohalogenations of HDDA Benzynes: An Approach to Polycyclic Aryl Halides

Siddique Khan1, Beeraiah Baire1

  • 1Department of Chemistry, Indian Institute of Technology Madras, Chennai 600036, Tamil Nadu, India.

Organic Letters
|September 18, 2024
PubMed
Summary

This study introduces a new method for synthesizing complex aryl halides using hydrohalogenation reactions of benzynes. Bismuth(III) halides facilitate this process, with regioselectivity controlled by substrate substituents.

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