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Unilateral adrenal Castleman's disease: A case report
Ji Li1, Jing Bai1, Haifeng Wang2
1Dept.of Urology, Yunnan Dehong People's Hospital, Dehong, Yunnan, 678400, China.
Urology Case Reports
|September 25, 2024
Summary
Castleman disease (CD) is a rare hematological disorder. This paper details a unique case of adrenal Castleman disease, highlighting its rarity and successful surgical treatment.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Castleman disease (CD) is a rare, heterogeneous hematological disorder with unclear etiology and nonspecific symptoms.
- While CD commonly affects the mediastinum, adrenal involvement is exceptionally rare, often presenting as an incidental finding.
- Distinguishing adrenal CD from common adrenal tumors on imaging is challenging, requiring pathological confirmation.
Observation:
- This report focuses on a rare case of a left adrenal mass incidentally discovered during a physical examination.
- The adrenal mass presented diagnostic challenges, mimicking common adrenal neoplasms on initial imaging studies.
Findings:
- Histopathological examination following surgical resection confirmed the diagnosis of Castleman disease in the adrenal mass.
- The patient underwent surgical intervention, which is the standard treatment for adrenal CD.
Implications:
- This case underscores the importance of considering Castleman disease in the differential diagnosis of adrenal masses, despite its rarity.
- Early diagnosis and surgical management of adrenal Castleman disease lead to a favorable prognosis.
- Further research into the etiology and specific diagnostic markers for adrenal CD is warranted.

