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Updated: Jun 12, 2025

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Visible-Light-Promoted Reduction of Nitroarenes with Formate Salts as Reductants

Jun-Yue Wu1, Yuan-Cui Wan1, Yu Shao1

  • 1College of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, China.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|September 26, 2024
PubMed
Summary

A new visible-light method efficiently reduces nitrobenzenes to anilines using formate salts. This transition metal-free reaction proceeds via radical intermediates, offering a green synthetic strategy.

Keywords:
Carbon dioxide radical anionFormate saltsNitrobenzenePhoto-inducedThiol

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