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Updated: Jun 12, 2025

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
Published on: June 12, 2021
Polymeric antibubbles with strong ultrasound imaging capabilities
Roman A Barmin1, Jens Köhler2, Michael Pohl2
1Institute for Experimental Molecular Imaging, RWTH Aachen University Hospital, Aachen 52074, Germany. rmoltopallar@ukaachen.de.
Abstract:
Antibubbles are liquid droplets encapsulated by a gas film that have recently been explored for on-demand ultrasound-triggered drug release. However, their ultrasound imaging capabilities are limited by their stiff shells stabilized with silica nanoparticles. Here, we develop polymeric antibubbles that generate greater ultrasound contrast than silica-based antibubbles, while showing better stability than conventional polymeric microbubbles.
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