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Updated: Jun 11, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate

Published on: June 21, 2017

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Palladium-Catalyzed Branch-Selective Allylic C-H Amination Enabled by Nucleophile Coordination

Zhong-Sheng Nong1, Pu-Sheng Wang1, Qi-Lin Zhou2

  • 1Hefei National Research Center for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.

Organic Letters
|September 27, 2024
PubMed
Summary

This study introduces a new method for selective C-H amination of alkenes using palladium catalysis. The developed phosphoramidite-palladium system efficiently produces allylamines with good regioselectivity.

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