Related Experiment Video
Updated: Jun 11, 2025
08:53
Assessing Neuroprotective Effects of Glycyrrhizae Radix et Rhizoma Extract Using a Transient Middle Cerebral Artery Occlusion Mouse Model
Published on: December 9, 2018
7.3K
[Licorice consumption can be life-threatening]
Olafur Orri Sturluson1, Birgir Johannsson1, Helga Agusta Sigurjonsdottir2
1Department of Medicine, Landspitali University Hospital.
Laeknabladid
|September 27, 2024
Summary
Excessive liquorice consumption can cause severe hypokalemia and hypertension. This case highlights liquorice-induced hypertension and apparent mineralocorticoid excess, emphasizing clinical awareness of this risk.
Area of Science:
- Endocrinology
- Nephrology
- Toxicology
Background:
- Liquorice contains glycyrrhizic acid, a compound that mimics mineralocorticoids.
- Excessive consumption can lead to electrolyte imbalances and hypertension.
Observation:
- A 71-year-old male presented with hypokalemia (2.1 mmol/L), muscle weakness, and new-onset hypertension.
- He reported consuming over 250g of liquorice daily.
- Investigations revealed atrial fibrillation, increased urinary potassium excretion, and suppressed renin and aldosterone levels.
Findings:
- The patient was diagnosed with liquorice-induced hypertension and apparent mineralocorticoid excess (pseudohyperaldosteronism).
- Influenza A infection was also noted but considered secondary to the primary endocrine disturbance.
Implications:
- Clinicians must consider excessive liquorice intake in patients presenting with hypokalemia and hypertension.
- Awareness of liquorice toxicity is crucial for accurate diagnosis and management of mineralocorticoid excess syndromes.
Keywords:
aldosteronegervi aldosteron heilkennilicorice poisoningliquoriceliquorice induced hypertensionpseudo-hyperaldosteronismMore Related Videos
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