Related Experiment Video
Updated: Jun 11, 2025

Electrochemical Preparation of Poly3,4-Ethylenedioxythiophene Layers on Gold Microelectrodes for Uric Acid-Sensing Applications
Published on: July 28, 2021
Pain-free today, weak tomorrow: a case of electrolyte disorder due to diclofenac misuse
Oriana De Marco1, Pasquale Buonanno2, Eleonora Riccio1
1Department of Public Health, Chair of Nephrology, University Federico II of Naples, Via Pansini 5, Naples, 80131, Italy.
Background:
The nephrotoxic effects of non-steroidal anti-inflammatory drugs (NSAIDs) are widely acknowledged. In particular, diclofenac is the most commonly prescribed NSAIDs, but no previous findings of electrolyte disturbances were reported following its administration.
Case Report:
We presented the case of a man who experienced significant weakness associated with severe deficiencies in potassium, calcium, and magnesium after misusing diclofenac because of severe back pain.
Conclusions:
This case emphasizes the need of awareness about the electrolyte imbalances and electrolyte disturbances associated with the misuse of diclofenac, which is a widely available drug. This is a case report which does not need a Clinical Trial Number.
Related Concept Videos
Ionic Bonds
When atoms gain or lose electrons to achieve a more stable electron configuration they form ions. Ionic bonds are electrostatic attractions between ions with opposite charges. Ionic compounds are rigid and brittle when solid and may dissociate into their constituent ions in water. Covalent compounds, by contrast, remain intact unless a chemical reaction breaks them.
Opposing Charges Hold Ions Together in Ionic Compounds
Ionic bonds are reversible electrostatic interactions between ions...
Disorder of Water Balance
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Introduction to Electrolytes
Role of Sodium
One...
Antihypertensive Drugs: Potassium-Sparing Diuretics
Acute Kidney Injury VI: Nursing Management
Dysrhythmias V: Evaluating Dysrhythmias

