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Design of bifunctional molecules to accelerate post-translational modifications: achievements and challenges

Yuxuan Wang1, Yanyi He1, Qidong You1

  • 1State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.

Drug Discovery Today
|September 29, 2024
PubMed
Abstract

Keywords:
bifunctional moleculeseffector selectionligand discoverymolecule design strategiesprotein post-translational modifications

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