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Quantifying Cognitive Decrements Caused by Cranial Radiotherapy
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Neuropsychological Evaluation for Oncology.

David P Sheppard1, Kyle R Noll2, Jeffrey S Wefel2

  • 1Department of Rehabilitation Medicine, University of Washington, 1959 Northeast Pacific Street Box 356490, Seattle, WA 98195, USA.

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Cancer treatments and cancer itself can cause cognitive dysfunction. Neuropsychological evaluations identify these changes, and interventions can help manage cognitive effects on daily life.

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Area of Science:

  • Oncology
  • Neuroscience
  • Psychology

Background:

  • Cognitive dysfunction is a frequent issue for cancer patients.
  • Multiple factors contribute, including cancer effects, treatments (surgery, radiation, systemic therapy), comorbidities, fatigue, and mood disturbances.

Purpose of the Study:

  • To outline the contributing factors to cancer-related cognitive dysfunction.
  • To highlight the role of neuropsychological evaluation in assessing cognitive function.
  • To emphasize the potential of cognitive interventions.

Main Methods:

  • Utilizing objective, validated measures for neuropsychological evaluation.
  • Assessing various cognitive domains relevant to patient history.

Main Results:

  • Neuropsychological evaluations provide insights into cognitive function patterns.
  • The specific cognitive domains assessed are tailored to individual patient histories.

Conclusions:

  • Cognitive dysfunction is a significant challenge in cancer care.
  • Neuropsychological assessment is crucial for understanding and managing these deficits.
  • Cognitive interventions offer a means to mitigate the impact on patients' daily lives.