Clinical Features and Outcomes of Long-Term Lead Performance by Left Bundle Branch Pacing.
Yi-Wen Pan1, Xiang Zhou1, Chan Yu2
1Department of Cardiology, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University.
Left bundle branch pacing (LBBP) is a safe and effective technique for atrioventricular block. Long-term outcomes show stable parameters and improved heart function in select patients, though mechanical complications can occur.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Left bundle branch pacing (LBBP) is an emerging physiological pacing method.
- Long-term safety and feasibility data for LBBP require further evaluation.
Purpose of the Study:
- To assess the long-term lead performance and clinical outcomes of LBBP.
- To identify factors associated with mechanical complications in LBBP.
Main Methods:
- Retrospective analysis of 123 consecutive patients undergoing LBBP implantation.
- Tracking of pacing parameters, ECG, echocardiography, and complications at implant and follow-up.
Main Results:
- Successful LBBP in 89.4% of patients.
- Improved left ventricular dimensions and ejection fraction in patients with reduced baseline LVEF.
- LBBP parameters remained stable; mechanical complications were linked to lower BMI, diabetes, and thinner interventricular septum.
Conclusions:
- LBBP is a safe, effective, and physiological pacing option for atrioventricular block.
- Long-term lead performance is stable, with functional improvements observed in specific patient groups.
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