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Early Diagnosis of Neonatal Sepsis Using Hematological Profiles
Nanda J Patil1, Shreya Tuli1, Sujata R Kanetkar1
1Department of Pathology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth Deemed to be University, Karad, Maharashtra, India.
Journal of Pharmacy & Bioallied Sciences
|September 30, 2024
Summary
Analyzing platelet count (PC) and indices can improve prognosis for neonatal sepsis (NN-SP) in preterm infants. Early identification is cost-effective, reducing mortality and morbidity.
Area of Science:
- Neonatology
- Pediatric Infectious Diseases
- Hematology
Background:
- Neonatal sepsis (NN-SP) poses a significant risk to preterm and extremely low-birth-weight newborns.
- Risk factors include intrapartum fever, premature rupture of membranes (PROM), and early-life sepsis.
- Pathogens can be acquired via intrauterine transmission or maternal flora.
Purpose of the Study:
- To evaluate the role of platelet count (PC) and its indices in neonatal sepsis (NN-SP).
- To determine if PC analysis can improve the prognosis of sepsis in newborns.
- To assess the cost-effectiveness of using PC for early identification of NN-SP.
Main Methods:
- Retrospective analysis of neonatal sepsis cases.
- Evaluation of platelet count (PC) and related indices.
- Correlation of PC findings with clinical outcomes.
Main Results:
- Platelet count (PC) analysis shows potential in improving sepsis prognosis.
- Early identification of NN-SP through PC can reduce mortality and morbidity.
- This diagnostic approach is cost-effective.
Conclusions:
- Analyzing platelet count (PC) and its indices is a valuable tool for managing neonatal sepsis (NN-SP).
- Early detection via PC analysis aids in reducing medical costs and improving patient outcomes.
- Clinical correlation with PC indicators offers a cost-effective strategy for preventing mortality and morbidity in newborns.

