Exploring the concept of disease control in chronic cough
Jin Young Park1, Haesung Jun1, Seung-Eun Lee2
1University of Ulsan College of Medicine, Seoul, South Korea.
ERJ Open Research
|October 1, 2024
Summary
Defining disease control in chronic cough is crucial. Patient-reported cough control correlates with severity and quality of life impact, but current tools may not fully capture it, necessitating further research.
Area of Science:
- Pulmonology
- Clinical Research
- Patient-Reported Outcomes
Background:
- Disease control is key in chronic diseases, yet a consensus definition for chronic cough is lacking.
- This study explores the concept of patient-reported cough control in chronic cough.
- Understanding patient perspectives is vital for effective chronic disease management.
Purpose of the Study:
- To conceptually explore patient-reported cough control in chronic cough.
- To identify factors relevant to cough control from both patient and physician viewpoints.
- To assess the correlation between patient-reported cough control and established outcome measures.
Main Methods:
- Two subanalyses were conducted involving patients with chronic cough.
- Correlation analyses examined patient-reported cough control against cough-specific and generic patient-reported outcomes (PROs).
- A survey of patients with refractory chronic cough and physicians identified key factors for cough control.
Main Results:
- Patient-reported cough control moderately correlated with cough severity and Leicester Cough Questionnaire scores.
- Weaker correlations were observed with cough-related symptoms, complications, and general quality of life (QoL).
- Patients and physicians agreed on factors like frequency, severity, and QoL impact, but patients prioritized the need for rescue medication.
Conclusions:
- Patient-reported cough control is linked to cough severity and QoL impact.
- Conventional PRO tools may not fully encompass the concept of cough control.
- Further research is needed to establish consensus and develop measurement tools for chronic cough disease control.
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