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Updated: Jan 26, 2026

Detection and Enrichment of Rare Antigen-specific B Cells for Analysis of Phenotype and Function
Published on: February 16, 2017
[Effect of bacterial antigens on the functional capacity of immunocompetent cells]
Abstract:
The study of some characteristics of the immune status of healthy donors has revealed that the quantitative characteristics of T-, B- and O-cells directly correlate with the total content of lymphocytes in the peripheral blood. Essential differences in the values of the characteristics indicating the natural resistance of the body (C'H50, IgM, phagocytic activity, phagocytic index) in the donors with a lower or higher (in comparison with the average value) level of lymphocytes in the peripheral blood. In healthy donors no essential changes in the capacity of T- and B-lymphocytes for rosette formation after their incubation with Pseudomonas aeruginosa have been detected.
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