RELATIONSHIP BETWEEN THE HEIGHT OF WIDE AND NARROW PRIMARY MACULAR STAPHYLOMA AND MYOPIC MACULAR RETINOSCHISIS

Area of Science:

• Ophthalmology
• Retinal Diseases
• High Myopia Research

Background:

• High myopia is a leading cause of visual impairment.
• Macular staphyloma is a common complication of high myopia.
• Myopic macular retinoschisis is a vision-threatening condition associated with high myopia.

Purpose of the Study:

• To determine the association between macular staphyloma depth and myopic macular retinoschisis.
• To identify risk factors for developing myopic macular retinoschisis in eyes with staphyloma.

Main Methods:

• Cross-sectional study of 69 highly myopic eyes with macular staphyloma.
• Classification into groups based on presence/absence of myopic macular retinoschisis using swept-source optical coherence tomography.
• Macular staphyloma depth measured by ocular ultrasonography (B-scan).

Main Results:

• 13.04% of eyes (9/69) exhibited myopic macular retinoschisis.
• Increased risk of retinoschisis was associated with vitreomacular traction (OR 11.32), arteriolar traction (OR 6.23), and greater staphyloma depth (OR 3.37).
• No significant difference in best-corrected visual acuity between groups.

Conclusions:

• Macular staphyloma depth is a novel and significant factor in the development of myopic macular retinoschisis.
• Vitreomacular and arteriolar traction are also associated with increased risk.
• Further research may elucidate the precise mechanisms linking staphyloma depth to retinoschisis.