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Updated: May 5, 2026

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Murine Model of Central Venous Stenosis using Aortocaval Fistula with an Outflow Stenosis
Published on: July 11, 2019
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Features associated with arteriovenous fistula patency. A meta-analysis
Dongjuan Zhang1, Jing Liang2, Yang Yang1
1Hemodialysis Center, 981th Hospital of Joint Logistic Support Force of Chinese People's Liberation Army, Chengde, Hebei, China.
Summary
Early arteriovenous fistula cannulation is linked to lower patency. Using plastic cannulas during initial puncture weeks can mitigate this effect, improving outcomes for hemodialysis access.
Area of Science:
- Nephrology
- Vascular Surgery
- Dialysis Access Management
Background:
- Arteriovenous fistulas (AVFs) are crucial for hemodialysis access.
- Cannulation-associated variables may impact AVF outcomes, but this is not well-established.
- Understanding these factors is vital for optimizing AVF longevity.
Purpose of the Study:
- To investigate the association between cannulation-associated variables and 1-year primary patency of AVFs.
- To determine if timing, technique, or needle type influences AVF success.
Main Methods:
- A meta-analysis of 28 publications was conducted.
- Studies included keywords related to AVF, patency, cannulation, and hemodialysis.
- Data on 1-year primary patency rates were extracted and analyzed.
Main Results:
- Early cannulation (less than 1.5 months post-creation) significantly reduced 1-year AVF primary patency (OR=0.41).
- Using plastic cannulas during the initial 2-3 weeks of cannulation attenuated the negative effect of early cannulation (OR=0.62 vs. 0.34).
- No significant difference in patency was found between upper arm and forearm fistulas, nor between buttonhole and rope-ladder cannulation techniques.
Conclusions:
- Early AVF cannulation is associated with decreased 1-year primary patency.
- The use of plastic cannulas in the initial cannulation period can mitigate the adverse effects of early cannulation on AVF patency.
- Further research may refine best practices for AVF cannulation to maximize long-term patency.

