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Respiratory sequelae after COVID-19 infection in Thai healthy children

Sirapoom Niamsanit1, Wicharn Boonjindasup1, Suchada Sritippayawan1

  • 1Division of Pulmonology and Critical Care, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Pediatric Pulmonology
|October 16, 2024
PubMed

Insights

Long COVID in children can cause lasting respiratory issues like fatigue and cough, with one in four experiencing symptoms. Pneumonia during COVID-19 infection increases the risk of these prolonged respiratory problems.

Area of Science:

  • Pediatric pulmonology
  • Infectious diseases
  • Public health

Background:

  • Long-term respiratory effects of COVID-19 in children are not well understood.
  • Variations in outcomes may exist globally.
  • This study focuses on Thai children to assess respiratory sequelae.

Purpose of the Study:

  • To investigate respiratory sequelae in children post-COVID-19 infection.
  • To identify residual respiratory symptoms and assess pulmonary function.
  • To determine factors associated with these long-term respiratory issues.

Main Methods:

  • Observational study of 56 children (7-18 years) with COVID-19.
  • Assessment of persistent symptoms up to 6 months post-infection.
  • Pulmonary function evaluation using spirometry.

Main Results:

  • 25% of children experienced post-COVID-19 symptoms (fatigue, cough, dyspnea).
  • Pneumonia was significantly correlated with post-COVID-19 symptoms (OR=6.00).
  • 17.8% showed abnormal pulmonary function, primarily obstructive impairment, with no significant clinical factor association.

Conclusions:

  • Prolonged respiratory symptoms and abnormal pulmonary function are common in children after COVID-19.
  • Post-COVID-19 symptoms may be linked to initial COVID-19 pneumonia.
Abstract

Keywords:
pediatricpost COVID‐19pulmonary function test

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