Exhaled Breath Analysis: From Laboratory Test to Wearable Sensing

Area of Science:

• Multidisciplinary scientific research
• Biomedical engineering
• Clinical diagnostics

Background:

• Breath analysis is crucial for managing respiratory and metabolic disorders.
• Advancements require integrating medicine, biology, engineering, and materials science.
• Current innovations focus on precise, real-time, in situ breath monitoring.

Purpose of the Study:

• To review the physical and chemical aspects of breath analysis.
• To highlight the physiological and clinical significance of breath constituents.
• To explore advanced laboratory and wearable sensing technologies.

Main Methods:

• Comprehensive literature review of breath analysis methodologies.
• Examination of laboratory testing techniques and wearable devices.
• Analysis of data processing in breathomics and human-machine interaction.

Main Results:

• Breath analysis encompasses respiratory parameters, volatile, and non-volatile compounds.
• Cutting-edge lab and wearable technologies enable precise monitoring.
• Sophisticated data processing is key to breathomics applications.

Conclusions:

• Interdisciplinary collaboration is vital for advancing breath analysis.
• Challenges remain in translating innovations to clinical practice.
• Non-invasive breath methodology holds potential for personalized medicine.