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Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
Published on: August 20, 2018
Synthesis and structural confirmation of selaginpulvilin X
Tereza Havlíková1, Sundaravelu Nallappan1, Ivana Císařová2
1Department of Organic Chemistry, Faculty of Science, Charles University, Hlavova 8, 128 00 Prague, Czech Republic. rycekl@natur.cuni.cz.
Abstract:
We report the first total synthesis of the natural product selaginpulvilin X, a selaginellaceae polyphenol class of compounds. Our synthetic strategy employs cross-coupling reactions and an organolithium addition to construct the carbon framework. Subsequently, the functional group modifications and deprotection yield the natural product. Spectral analysis confirms the proposed structure by comparing natural and synthetic samples.

