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Updated: Jun 10, 2025

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
Photochemically Driven Palladium- Phosphinoacridine Catalysis: A Carboxylative Approach for Arylcarbamate Synthesis
Renhe Tang1, Yi Yang1, Seifallah Abid1
1Univ Lyon, CNRS, Université Claude Bernard Lyon 1, ICBMS, UMR5246, 43 Bd du 11 Novembre 1918, 69622, Villeurbanne, France.
Abstract:
In this study, we demonstrate that phosphinoacridines are efficient bidentate ligands for palladium-catalyzed carboxylative C-N coupling reactions under blue LED irradiation. This method facilitates the direct synthesis of arylcarbamates using a range of non-activated aryl halides, such as iodides and bromides, with various amines under atmospheric pressure of CO2. The optimized conditions exhibit high tolerance to sensitive functional groups, resulting in very good to excellent yields of the desired products. This approach expands the scope of palladium-catalyzed carboxylation reactions and offers an environmentally friendly route to arylcarbamates.
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